MBC
1,8-二羟基-3-甲基蒽-9,10-二酮|Chrysophanic Acid
| PB00630-100mg
純度: 98%
M0703-79415
PB00630-100mg
100mg
481-74-3
C15H10O4
98%
¥314.00
¥195.00
1
3 天
售前咨询：sales@ygsci.com
电话咨询：4000-876-099
- 产品详情
昀冠品质提供的1,8-二羟基-3-甲基蒽-9,10-二酮 MBC(PB00630-100mg) 性能卓越，竭诚为您服务。
| 英文名称* | Chrysophanic Acid |
|---|---|
| 中文名称 | 1,8-二羟基-3-甲基蒽-9,10-二酮 |
| 别名 | Chrysophanol, Turkey Rhubarb, 3-Methylchrysazin |
| 产品描述 | Chrysophanic acid is an EGFR/mTOR pathway inhibitor, which can be found in rhubarb, and sorrel. |
| 靶点活性 | EGFR |
| 体内活性 | Chrysophanol (CA) improves HFD-induced obesity in C57BL/6 Mice. The in vivo performance of Chrysophanol is performed in male C57BL/6J mice to determine the efficacy of administered Chrysophanol. Mice fed the HFD gained significantly more weight than those fed the standard diet mice. On the other hand, weight gain of Chrysophanol group is significantly less than with the untreated HFD. Mice in the HFD-group gained 23.92 ± 1.74 g of weight, while those in the Chrysophanol group gained 16.72±2 g of weight after 16 weeks[3]. |
| 细胞实验 | Chrysophanol (Chrysophanic Acid) is dissolved in DMSO and stored, and then diluted with appropriate medium before use[1]. The cells are seeded at 5×103 cells/mL in 96-well microplates and allowed to attach for 24 h. Chrysophanol (20, 50, 80 and 120 μM) is added to the medium at various concentrations up to 120 μM and for different durations. After treatment, cell cytotoxicity and/or proliferation is assessed by a Cell Counting Kit-8 (CCK-8). Briefly, highly water-soluble tetrazolium salt, WST-8, produces an orange colored water-soluble product, formazan. The amount of formazan dye generated by dehydrogenases in cells is directly proportional to the number of living cells.CCK-8 (10 μL) is added to each well and incubated for 3 h at 37°C, then cell proliferation and cytotoxicity are assessed by measuring the absorbance at 450 nm using a microplate reader.Three replicated wells are used for each experimental condition[1]. |
| CAS | 481-74-3 |
| 纯度 | 98% |
| 分子量 | 254.24 |
| 分子式 | C15H10O4 |
| 溶解度 | DMSO: 5 mg/mL (19.66 mM), warmed Ethanol: <1 mg/mL Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble ) |
| 储存温度 | 0-4℃ for short term (days to weeks), or -20℃ for long term (months). |
| 品牌 | MBC |
作为众多知名品牌的合作伙伴，昀冠以专业技术和热情服务与您携手建立战略合作。
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用
